Lowest price guarantee - We will beat any price!
Free worldwide shipping for orders over $50
855 908 4010
15003 testimonials ...and counting 4.97

Trifexis vs Heartgard

Compare Trifexis Tablets to Heartgard Plus Chewables

Once established in your dog, heartworm disease can be difficult and costly to eradicate. However, preventing this dangerous canine parasite can be as simple as administering a monthly oral treatment.

Trifexis and Heartgard Plus both provide month-long protection against the development of heartworm, as well as preventing hookworms and roundworms. Trifexis has the additional benefit of protecting against whipworms, and treating flea infestations by killing adult fleas, eggs and larvae.

Trifexisis for use only with dogs and puppies at least 8 weeks of age, weighing 5 lbs (2.3kg) minimum.Heartgard Plus may be given to dogs and puppies from 6 weeks, with no weight restrictions.

As with all medications, you should consider if these products are suitable for your dog’s needs. Trifexis has not been tested as safe for use with breeding males, and should be used with caution on pregnant females. When used as directed, Heartgard Plus is safe for use with pregnant and breeding dogs.

Top tip: Fleas and ticks can carry nasty diseases, but protecting your pet doesn’t need to be difficult. Use our comparison chart to weigh up the pros and cons of the most popular products.

  Trifexis Heartgard Plus
Kills Fleas yes tick -
Repels Fleas - -
Kills Flea Eggs and Larvae yes tick -
Prevents Heartworm yes tick yes tick
Prevents Roundworms yes tick yes tick
Prevents Hookworms yes tick yes tick
Prevents Whipworms yes tick -
Other Parasites    
Safe for Pregnant or Nursing Pets - yes tick
When does it starts working Kills fleas within 30 minutes; kills 100% of fleas within 4 hours Begins working Immediately
Application Beef-flavored tablet Beef-flavored chewable
Active Ingredient(s) Spinosad, Milbemycin Oxime Ivermectin, Pyrantel Pamoate
Dosage Monthly Monthly

Trifexis vs Heartgard

Sort By